HSPH1 Antibody

• Background:

  HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. This protein inhibits HSPA8/HSC70 ATPase and chaperone activities.

• NCBI Gene ID:

  10808

• Swiss Prot:

  Q92598

• Accession Number:

  Q92598

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HSPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-579 amino acids from the Central region of human HSPH1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  97 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  HSPH1

• NCBI Official Name:

  Heat shock protein 105 kDa

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ishihara K., Yasuda K., Hatayama T.Biochim. Biophys. Acta 1444:138-142 (1999)

• Background Reference 02:

  Nagase T., Seki N., Ishikawa K., Ohira M., Kawarabayasi Y., DNA Res. 3:321-329 (1996)

• Background Reference 03:

  The MGC Project Team Genome Res. 14:2121-2127 (2004)

• Background Reference 04:

  Miyazaki M., Nakatsura T., Yokomine K., Senju S., Monji M., Hosaka S., Cancer Sci. 96:695-705 (2005)

• Other Product Names:

  Heat shock protein 105 kDa, Antigen NY-CO-25, Heat shock 110 kDa protein, HSPH1, HSP105, HSP110, KIAA0201

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  2495344

• Physical Properties:

  Liquid