Methionine Aminopeptidase 2 Antibody

• Background:

  The ADP-ribosylation factor (Arf) family are highly conserved members of the Ras superfamily of regulatory GTP-binding proteins. Arf proteins participate in routing of intracellular proteins to and within the Golgi complex. Cellular functions include maintenance of organelle integrity, coat protein assembly, as an activator of phospholipase D. The Arf family is divided functionally into the Arf and the Arf-like (Arl) proteins. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization.

• NCBI Gene ID:

  10988

• Swiss Prot:

  P50579

• Accession Number:

  P50579

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Methionine Aminopeptidase 2 (METAP2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-467 amino acids from the C-terminal region of human Methionine Aminopeptidase 2 (METAP2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  53 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  METAP2

• NCBI Official Name:

  Methionine aminopeptidase 2 {ECO:0000255|HAMAP-Rule:MF_03175}

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wang, J., et al., Biochemistry 42 (17) :5035-5042 (2003) .

• Background Reference 02:

  Datta, R., et al., Exp. Cell Res. 283 (2) :237-246 (2003) .

• Background Reference 03:

  Endo, H., et al., J. Biol. Chem. 277 (29) :26396-26402 (2002) .

• Background Reference 04:

  Kanno, T., et al., Lab. Invest. 82 (7) :893-901 (2002) .

• Other Product Names:

  Methionine aminopeptidase 2 {ECO:0000255|HAMAP-Rule:MF_03175}, MAP 2 {ECO:0000255|HAMAP-Rule:MF_03175}, MetAP 2 {ECO:0000255|HAMAP-Rule:MF_03175}, 341118 {ECO:0000255|HAMAP-Rule:MF_03175}, Initiation factor 2-associated 67 kDa glycoprotein {ECO:0000255|HAMAP-Rule:MF_03175}, p67 {ECO:0000255|HAMAP-Rule:MF_03175}, p67eIF2 {ECO:0000255|HAMAP-Rule:MF_03175}, Peptidase M {ECO:0000255|HAMAP-Rule:MF_03175}, METAP2 {ECO:0000255|HAMAP-Rule:MF_03175}

• Tested Applications:

  WB, IHC-P

• Protein ID:

  1703273

• Physical Properties:

  Liquid