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ZNF238 Antibody

CAT: 0223-61-172Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-61-172Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'- [AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus.
NCBI Gene ID
10472
Swiss Prot
Q99592
Accession Number
Q99592
Host
Rabbit
Reactivity
Mouse
Immunogen
This ZNF238 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 318-331 amino acids from human ZNF238.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
ZBTB18
NCBI Official Name
Zinc finger and BTB domain-containing protein 18
NCBI Organism
Homo sapiens
Background Reference 01
Becker K.G., et al.Hum. Mol. Genet. 4:685-691 (1995) .
Background Reference 02
Aoki K., et al.J. Biol. Chem. 273:26698-26704 (1998) .
Background Reference 03
Meng G., et al.Gene 242:59-64 (2000) .
Background Reference 04
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Other Product Names
Zinc finger and BTB domain-containing protein 18, 58 kDa repressor protein, Transcriptional repressor RP58, Translin-associated zinc finger protein 1, TAZ-1, Zinc finger protein 238, Zinc finger protein C2H2-171, ZBTB18, RP58, TAZ1, ZNF238
Tested Applications
WB
Protein ID
20141020
Physical Properties
Liquid

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