STRADA Antibody

• Background:

  Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

• NCBI Gene ID:

  92335

• Swiss Prot:

  Q7RTN6

• Accession Number:

  Q7RTN6

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This STRADA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 303-346 amino acids from the C-terminal region of human STRADA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  STRADA

• NCBI Official Name:

  STE20-related kinase adapter protein alpha

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Scanlan M.J., et al.Cancer Immun. 1:4-4 (2001) .

• Background Reference 02:

  Shan Y.X., et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.

• Background Reference 03:

  Ota T., et al.Nat. Genet. 36:40-45 (2004) .

• Background Reference 04:

  Bechtel S., et al.BMC Genomics 8:399-399 (2007) .

• Other Product Names:

  STE20-related kinase adapter protein alpha, STRAD alpha, STE20-related adapter protein, Serologically defined breast cancer antigen NY-BR-96, STRADA, LYK5 {ECO:0000312|EMBL:AAP422801}, STRAD

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  74759034

• Physical Properties:

  Liquid