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TIAM1 Antibody

CAT: 0223-60-795Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-795Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
NCBI Gene ID
7074
Swiss Prot
Q13009
Accession Number
Q13009
Host
Rabbit
Reactivity
Human
Immunogen
This TIAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1478-1506 amino acids from the C-terminal region of human TIAM1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
178 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TIAM1
NCBI Official Name
T-lymphoma invasion and metastasis-inducing protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Yang, W., et al. Jpn. J. Clin. Oncol. 40 (11) :1053-1059 (2010)
Background Reference 02
Moriarty, C.H., et al. J. Biol. Chem. 285 (27) :20541-20546 (2010)
Background Reference 03
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 04
Rajagopal, S., et al. J. Biol. Chem. 285 (23) :18060-18071 (2010)
Other Product Names
T-lymphoma invasion and metastasis-inducing protein 1, TIAM-1, TIAM1
Tested Applications
WB
Protein ID
152031709
Physical Properties
Liquid

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