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MMP26 Antibody

CAT: 0223-60-765Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-765Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.
NCBI Gene ID
56547
Swiss Prot
Q9NRE1
Accession Number
Q9NRE1
Host
Rabbit
Reactivity
Human
Immunogen
This MMP26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human MMP26.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MMP26
NCBI Official Name
Matrix metalloproteinase-26
NCBI Organism
Homo sapiens
Background Reference 01
De Amorim, R.F., et al. Acta Odontol. Scand. 68 (4) :228-231 (2010)
Background Reference 02
Ban, J.Y., et al. Life Sci. 86 (19-20), 756-759 (2010) :
Background Reference 03
Deng, Y., et al. Oncol. Rep. 23 (1) :69-78 (2010)
Background Reference 04
Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :
Other Product Names
Matrix metalloproteinase-26, MMP-26, 3424-, Endometase, Matrilysin-2, MMP26
Tested Applications
WB
Protein ID
13629493
Physical Properties
Liquid

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