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JUN Antibody

CAT: 0223-60-744Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-744Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
JUN interacts directly with specific target DNA sequences to regulate gene expression. Jun recognizes the AP-1 consensus sequence TGACTCA, a response element that confers sensitivity to one of the tumor-promoting Phorbol esters, 12-O-tetradecanoyl-phorbol-13-acetate (see also: TRE, TPA response element) . Jun itself forms homodimers or heterodimers with junD and junB and also interacts with the oncogene product fos, forming jun-fos heterodimers.
NCBI Gene ID
3725
Swiss Prot
P05412
Accession Number
P05412
Host
Rabbit
Reactivity
Human
Immunogen
This JUN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from human JUN.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction, Inflammasomes
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
JUN
NCBI Official Name
Transcription factor AP-1
NCBI Organism
Homo sapiens
Background Reference 01
Fujita, S., J. Mol. Biol. 378 (3), 492-504 (2008)
Background Reference 02
Gan, X.Q., Cell Biol. 180 (6), 1087-1100 (2008)
Background Reference 03
Yogev, O., Cancer Res. 68 (5), 1398-1406 (2008)
Other Product Names
Transcription factor AP-1, Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39, JUN
Tested Applications
WB
Protein ID
135298
Physical Properties
Liquid

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