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PPP2R1A Antibody

CAT: 0223-60-680Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-680Size:400 µL
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Background
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq].
NCBI Gene ID
5518
Swiss Prot
P30153
Accession Number
P30153
Host
Rabbit
Reactivity
Human
Immunogen
This PPP2R1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-481 amino acids from the C-terminal region of human PPP2R1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
65 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPP2R1A
NCBI Official Name
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
NCBI Organism
Homo sapiens
Background Reference 01
Jones, S., et al. Science 330 (6001) :228-231 (2010)
Background Reference 02
Schmitz, M.H., et al. Nat. Cell Biol. 12 (9) :886-893 (2010)
Background Reference 03
Heikkinen, P.T., et al. J. Biol. Chem. 285 (6) :3740-3749 (2010)
Background Reference 04
Dupont, W.D., et al. Cancer 116 (1) :8-19 (2010)
Other Product Names
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Medium tumor antigen-associated 61 kDa protein, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha, PPP2R1A
Tested Applications
WB
Protein ID
143811355
Physical Properties
Liquid

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