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COLQ Antibody

CAT: 0223-60-634Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-634Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in this gene are associated with endplate acetylcholinesterase deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
8292
Swiss Prot
Q9Y215
Accession Number
Q9Y215
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This COLQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human COLQ.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
COLQ
NCBI Official Name
Acetylcholinesterase collagenic tail peptide
NCBI Organism
Homo sapiens
Background Reference 01
Mihaylova, V., et al. Brain 131 (PT 3), 747-759 (2008) :
Background Reference 02
Schreiner, F., et al. Neuromuscul. Disord. 17 (3) :262-265 (2007)
Background Reference 03
Ting, A.K., et al. Chem. Biol. Interact. 157-158, 63-70 (2005) :
Background Reference 04
Dvir, H., et al. EMBO J. 23 (22) :4394-4405 (2004)
Other Product Names
Acetylcholinesterase collagenic tail peptide, AChE Q subunit, Acetylcholinesterase-associated collagen, COLQ
Tested Applications
WB
Protein ID
116241309
Physical Properties
Liquid

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