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GTPBP3 Antibody

CAT: 0223-60-598Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-598Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.
NCBI Gene ID
84705
Swiss Prot
Q969Y2
Accession Number
Q969Y2
Host
Rabbit
Reactivity
Human
Immunogen
This GTPBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the Central region of human GTPBP3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GTPBP3
NCBI Official Name
TRNA modification GTPase GTPBP3, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Reiling, E., et al. Eur. J. Hum. Genet. 17 (8) :1056-1062 (2009)
Background Reference 02
Villarroya, M., et al. Mol. Cell. Biol. 28 (24) :7514-7531 (2008)
Background Reference 03
Bykhovskaya, Y., et al. Mol. Genet. Metab. 83 (3) :199-206 (2004)
Background Reference 04
Li, X., et al. Biochem. Biophys. Res. Commun. 312 (3) :747-754 (2003)
Other Product Names
TRNA modification GTPase GTPBP3, mitochondrial, GTP-binding protein 3, Mitochondrial GTP-binding protein 1, GTPBP3, MTGP1
Tested Applications
WB
Protein ID
313104112
Physical Properties
Liquid

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