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Cleavage stimulation factor 2 Antibody

CAT: 0223-60-542Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-542Size:400 µL
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Background
CSTF2 is one of three (including CSTF1 and CSTF3) cleavage stimulation factors which combine to form CSTF which is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. CSTF2 contains a ribonucleoprotein-type RNA binding domain. CSTF2 is upregulated during activation of B cells which results in the switch of IgM heavy chain mRNA from membrane bound form to the secreted form.
NCBI Gene ID
1478
Swiss Prot
P33240
Accession Number
P33240
Host
Rabbit
Reactivity
Human
Immunogen
This Cleavage stimulation factor 2 (CSTF2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human Cleavage stimulation factor 2 (CSTF2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CSTF2
NCBI Official Name
Cleavage stimulation factor subunit 2
NCBI Organism
Homo sapiens
Background Reference 01
Takagaki, Y., et al., Mol. Cell 2 (6) :761-771 (1998) .
Background Reference 02
Martincic, K., et al., Proc. Natl. Acad. Sci. U.S.A. 95 (19) :11095-11100 (1998) .
Background Reference 03
Takagaki, Y., et al., Cell 87 (5) :941-952 (1996) .
Background Reference 04
Takagaki, Y., et al., Nature 372 (6505) :471-474 (1994) .
Other Product Names
Cleavage stimulation factor subunit 2, CF-1 64 kDa subunit, Cleavage stimulation factor 64 kDa subunit, CSTF 64 kDa subunit, CstF-64, CSTF2
Tested Applications
WB
Protein ID
461847
Physical Properties
Liquid