Cleavage stimulation factor 2 Antibody

• Background:

  CSTF2 is one of three (including CSTF1 and CSTF3) cleavage stimulation factors which combine to form CSTF which is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. CSTF2 contains a ribonucleoprotein-type RNA binding domain. CSTF2 is upregulated during activation of B cells which results in the switch of IgM heavy chain mRNA from membrane bound form to the secreted form.

• NCBI Gene ID:

  1478

• Swiss Prot:

  P33240

• Accession Number:

  P33240

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Cleavage stimulation factor 2 (CSTF2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human Cleavage stimulation factor 2 (CSTF2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CSTF2

• NCBI Official Name:

  Cleavage stimulation factor subunit 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Takagaki, Y., et al., Mol. Cell 2 (6) :761-771 (1998) .

• Background Reference 02:

  Martincic, K., et al., Proc. Natl. Acad. Sci. U.S.A. 95 (19) :11095-11100 (1998) .

• Background Reference 03:

  Takagaki, Y., et al., Cell 87 (5) :941-952 (1996) .

• Background Reference 04:

  Takagaki, Y., et al., Nature 372 (6505) :471-474 (1994) .

• Other Product Names:

  Cleavage stimulation factor subunit 2, CF-1 64 kDa subunit, Cleavage stimulation factor 64 kDa subunit, CSTF 64 kDa subunit, CstF-64, CSTF2

• Tested Applications:

  WB

• Protein ID:

  461847

• Physical Properties:

  Liquid