CCDC6 Antibody

• Background :

  This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.

• NCBI Gene ID :

  8030

• Swiss Prot :

  Q16204

• Accession Number :

  Q16204

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CCDC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the N-terminal region of human CCDC6.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  53 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  CCDC6

• NCBI Official Name :

  Coiled-coil domain-containing protein 6

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Leone, V., et al. Oncogene 29 (30) :4341-4351 (2010)

• Background Reference 02 :

  Richardson, D.S., et al. Cancer Res. 69 (11) :4861-4869 (2009)

• Background Reference 03 :

  Jazdzewski, K., et al. Proc. Natl. Acad. Sci. U.S.A. 105 (20) :7269-7274 (2008)

• Background Reference 04 :

  Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

• Other Product Names :

  Coiled-coil domain-containing protein 6, Papillary thyroid carcinoma-encoded protein, Protein H4, CCDC6, D10S170, TST1

• Tested Applications :

  WB

• Protein ID :

  292494979

• Physical Properties :

  Liquid