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KCNIP2 Antibody

CAT: 0223-60-491Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-491Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene. [provided by RefSeq].
NCBI Gene ID
30819
Swiss Prot
Q9NS61
Accession Number
Q9NS61
Host
Rabbit
Reactivity
Human
Immunogen
This KCNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human KCNIP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KCNIP2
NCBI Official Name
Kv channel-interacting protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Foeger, N.C., et al. J. Biol. Chem. 285 (43) :33413-33422 (2010)
Background Reference 02
Lundby, A., et al. Br. J. Pharmacol. 160 (8) :2028-2044 (2010)
Background Reference 03
Levy, D.I., et al. J. Physiol. (Lond.) 588 (PT 14), 2657-2668 (2010) :
Background Reference 04
Cotella, D., et al. Pflugers Arch. 460 (1) :87-97 (2010)
Other Product Names
Kv channel-interacting protein 2, KChIP2, A-type potassium channel modulatory protein 2, Cardiac voltage-gated potassium channel modulatory subunit, Potassium channel-interacting protein 2, KCNIP2, KCHIP2
Tested Applications
WB
Protein ID
338817979
Physical Properties
Liquid

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