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SLC25A20 Antibody

CAT: 0223-60-334Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-334Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.
NCBI Gene ID
788
Swiss Prot
O43772
Accession Number
O43772
Host
Rabbit
Reactivity
Mouse
Immunogen
This SLC25A20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from the C-terminal region of human SLC25A20.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SLC25A20
NCBI Official Name
Mitochondrial carnitine/acylcarnitine carrier protein
NCBI Organism
Homo sapiens
Background Reference 01
Tachibana, K., et al. Biochem. Biophys. Res. Commun. 389 (3) :501-505 (2009)
Background Reference 02
De Lucas, J.R., et al. Mol. Membr. Biol. 25 (2) :152-163 (2008)
Background Reference 03
Pierre, G., et al. J. Inherit. Metab. Dis. 30 (5), 815 (2007) :
Background Reference 04
Peluso, G., et al. J. Cell. Physiol. 203 (2) :439-446 (2005)
Other Product Names
Mitochondrial carnitine/acylcarnitine carrier protein, Carnitine/acylcarnitine translocase, CAC, Solute carrier family 25 member 20, SLC25A20, CAC, CACT
Tested Applications
WB
Physical Properties
Liquid

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