GNB4 Antibody

• Background:

  Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.

• NCBI Gene ID:

  59345

• Swiss Prot:

  Q9HAV0

• Accession Number:

  Q9HAV0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GNB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human GNB4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Zebrafish, Drosophila, Mouse, Rat, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  38 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GNB4

• NCBI Official Name:

  Guanine nucleotide-binding protein subunit beta-4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Riemann, K., et al. Anticancer Res. 29 (4) :1271-1274 (2009)

• Background Reference 02:

  Riemann, K., et al. Pharmacogenet. Genomics 18 (11) :999-1008 (2008)

• Background Reference 03:

  Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

• Background Reference 04:

  Rosskopf, D., et al. FEBS Lett. 544 (1-3), 27-32 (2003) :

• Other Product Names:

  Guanine nucleotide-binding protein subunit beta-4, Transducin beta chain 4, GNB4

• Tested Applications:

  WB

• Protein ID:

  22256759

• Physical Properties:

  Liquid