GPR39 Antibody

• Background:

  Zn (2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G (q) -alpha and G (12) /G (13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity) .

• NCBI Gene ID:

  2863

• Swiss Prot:

  O43194

• Accession Number:

  O43194

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GPR39 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-407 amino acids from the C-terminal region of human GPR39.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GPR39

• NCBI Official Name:

  G-protein coupled receptor 39

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sharir, H., et al. J. Biol. Chem. 285 (34) :26097-26106 (2010)

• Background Reference 02:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03:

  Holst, B., et al. J. Biol. Chem. 285 (6) :3973-3985 (2010)

• Background Reference 04:

  Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :

• Other Product Names:

  G-protein coupled receptor 39, GPR39

• Tested Applications:

  WB

• Physical Properties:

  Liquid