Products for Research Use Only
RegisterLogin

ALDOB Antibody

CAT: 0223-60-153Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-60-153Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq].
NCBI Gene ID
229
Swiss Prot
P05062
Accession Number
P05062
Host
Rabbit
Reactivity
Human
Immunogen
This ALDOB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human ALDOB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ALDOB
NCBI Official Name
Fructose-bisphosphate aldolase B
NCBI Organism
Homo sapiens
Background Reference 01
Bouteldja, N., et al. J. Inherit. Metab. Dis. 33 (2) :105-112 (2010)
Background Reference 02
Coffee, E.M., et al. J. Inherit. Metab. Dis. 33 (1) :33-42 (2010)
Background Reference 03
Segat, L., et al. J. Gastroenterol. Hepatol. 24 (12) :1840-1846 (2009)
Background Reference 04
Davit-Spraul, A., et al. Mol. Genet. Metab. 94 (4) :443-447 (2008)
Other Product Names
Fructose-bisphosphate aldolase B, Liver-type aldolase, ALDOB, ALDB
Tested Applications
WB
Protein ID
113611
Physical Properties
Liquid

Related Products

CatalogName
61-467ALDOC Antibody
30-356ALDOA Antibody
70-936ALDOC Antibody
14-068ALDOC Antibody
14-017ALDOA Antibody
55-626ALDOC Antibody
43-552ALDOA Antibody
43-518ALDOA Antibody
30-388ALDOC Antibody
61-457ALDOA Antibody

Alternative Products

CatalogName
GTR18123088ALDOB Antibody

Popular Products