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TBC1D2 Antibody

CAT: 0223-59-995Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-995Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TBC1D2 acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivativation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
NCBI Gene ID
55357
Swiss Prot
Q9BYX2
Accession Number
Q9BYX2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TBC1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-465 amino acids from the Central region of human TBC1D2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
105 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TBC1D2
NCBI Official Name
TBC1 domain family member 2A
NCBI Organism
Homo sapiens
Background Reference 01
Letra, A., et al. Am. J. Med. Genet.152A (7), 1701-1710 (2010) :
Background Reference 02
Ishibashi, K., et al. Genes Cells 14 (1) :41-52 (2009)
Background Reference 03
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Background Reference 04
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (33) :12130-12135 (2004)
Other Product Names
TBC1 domain family member 2A, Armus, Prostate antigen recognized and identified by SEREX 1, PARIS-1, TBC1D2, PARIS1, PP8997, TBC1D2A
Tested Applications
WB
Protein ID
300669706
Physical Properties
Liquid

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