RAB40C Antibody

• Background:

  Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

• NCBI Gene ID:

  57799

• Swiss Prot:

  Q96S21

• Accession Number:

  Q96S21

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This RAB40C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-148 amino acids from the Central region of human RAB40C.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  31 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RAB40C

• NCBI Official Name:

  Ras-related protein Rab-40C

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ng, E.L., et al. Brain Res Rev 58 (1) :236-246 (2008)

• Background Reference 02:

  Lettre, G., et al. Nat. Genet. 40 (5) :584-591 (2008)

• Background Reference 03:

  Martin, J., et al. Nature 432 (7020) :988-994 (2004)

• Background Reference 04:

  Kile, B.T., et al. Trends Biochem. Sci. 27 (5) :235-241 (2002)

• Other Product Names:

  Ras-related protein Rab-40C, Rar-like protein, Ras-like protein family member 8C, SOCS box-containing protein RAR3, RAB40C, RARL, RASL8C

• Tested Applications:

  WB

• Protein ID:

  27734457

• Physical Properties:

  Liquid