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LHX8 Antibody

CAT: 0223-59-950Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-950Size:400 µL
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Background
Members of the LIM homeobox gene family, such as LHX8, encode transcription regulators that share common structural features. They all contain 2 tandemly repeated cysteine-rich double-zinc finger motifs, called LIM domains, in addition to a homeodomain. The homeodomain is a DNA-binding domain, and the LIM domains are essential for regulating the activity of these molecules by interacting with other proteins. Members of the LIM homeobox gene family are required for the patterning or the specification and differentiation of different cell types during embryonic development (Zhao et al., 1999 [PubMed 10611327]) .
NCBI Gene ID
431707
Swiss Prot
Q68G74
Accession Number
Q68G74
Host
Rabbit
Reactivity
Human
Immunogen
This LHX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-232 amino acids from the Central region of human LHX8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LHX8
NCBI Official Name
LIM/homeobox protein Lhx8
NCBI Organism
Homo sapiens
Background Reference 01
Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (9) :748-756 (2010)
Background Reference 02
Jagomagi, T., et al. Eur. J. Oral Sci. 118 (3) :213-220 (2010)
Background Reference 03
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 04
Vieira, A.R., et al. Genet. Med. 10 (9) :668-674 (2008)
Other Product Names
LIM/homeobox protein Lhx8, LIM homeobox protein 8, LHX8
Tested Applications
WB
Protein ID
296434566
Physical Properties
Liquid

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