TXNDC5 Antibody

• Background:

  This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene.

• NCBI Gene ID:

  81567

• Swiss Prot:

  Q8NBS9

• Accession Number:

  Q8NBS9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TXNDC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the Central region of human TXNDC5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  TXNDC5

• NCBI Official Name:

  Thioredoxin domain-containing protein 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zhang, L., et al. J. Cancer Res. Clin. Oncol. 136 (10) :1497-1505 (2010)

• Background Reference 02:

  Jeong, K.H., et al. Br. J. Dermatol. 162 (4) :759-764 (2010)

• Background Reference 03:

  Charlton, H.K., et al. Biochem. Biophys. Res. Commun. 392 (2) :234-239 (2010)

• Background Reference 04:

  So, H.C., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (1), 103-113 (2010) :

• Other Product Names:

  Thioredoxin domain-containing protein 5, Endoplasmic reticulum resident protein 46, ER protein 46, ERp46, Thioredoxin-like protein p46, TXNDC5, TLP46

• Tested Applications:

  WB

• Protein ID:

  29839560

• Physical Properties:

  Liquid