DNAJC5 Antibody

• Background:

  This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8.

• NCBI Gene ID:

  80331

• Swiss Prot:

  Q9H3Z4

• Accession Number:

  Q9H3Z4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This DNAJC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the Central region of human DNAJC5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  22 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  DNAJC5

• NCBI Official Name:

  DnaJ homolog subfamily C member 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Johnson, J.N., et al. Biochem. Cell Biol. 88 (2) :157-165 (2010)

• Background Reference 02:

  Schmidt, B.Z., et al. J. Biol. Chem. 284 (7) :4168-4178 (2009)

• Background Reference 03:

  Greaves, J., et al. J. Biol. Chem. 283 (36) :25014-25026 (2008)

• Background Reference 04:

  Park, J., et al. Am. J. Respir. Cell Mol. Biol. 39 (1) :68-76 (2008)

• Other Product Names:

  DnaJ homolog subfamily C member 5, Cysteine string protein, CSP, DNAJC5, CSP

• Tested Applications:

  WB

• Protein ID:

  15213953

• Physical Properties:

  Liquid