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MR1 Antibody

CAT: 0223-59-122Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-122Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MR1 has antigen presentation function. Involved in the development and expansion of a small population of T cells expressing an invariant T cell receptor alpha chain called mucosal-associated invariant T cells (MAIT) . MAIT cells are preferentially located in the gut lamina propria and therfore may be involed in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.
NCBI Gene ID
3140
Swiss Prot
Q95460
Accession Number
Q95460
Host
Rabbit
Reactivity
Human
Immunogen
This MR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 amino acids from the C-terminal region of human MR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MR1
NCBI Official Name
Major histocompatibility complex class I-related gene protein
NCBI Organism
Homo sapiens
Background Reference 01
Gozalbo-Lopez, B., et al. Histol. Histopathol. 24 (11) :1439-1449 (2009)
Background Reference 02
Stumpf, A.N., et al. Blood 114 (17) :3684-3692 (2009)
Background Reference 03
Huang, S., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (20) :8290-8295 (2009)
Background Reference 04
Aldemir, H. Biochem. Biophys. Res. Commun. 366 (2) :328-334 (2008)
Other Product Names
Major histocompatibility complex class I-related gene protein, MHC class I-related gene protein, Class I histocompatibility antigen-like protein, MR1
Tested Applications
WB
Protein ID
74751679
Physical Properties
Liquid

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