Products for Research Use Only
RegisterLogin

KLHL12 Antibody

CAT: 0223-59-118Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-59-118Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
NCBI Gene ID
59349
Swiss Prot
Q53G59
Accession Number
Q53G59
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This KLHL12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human KLHL12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Zebrafish, Rat, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
63 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KLHL12
NCBI Official Name
Kelch-like protein 12
NCBI Organism
Homo sapiens
Background Reference 01
Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)
Background Reference 02
Rondou, P., et al. J. Biol. Chem. 283 (17) :11083-11096 (2008)
Background Reference 03
Lim, J., et al. Cell 125 (4) :801-814 (2006)
Background Reference 04
Angers, S., et al. Nat. Cell Biol. 8 (4) :348-357 (2006)
Other Product Names
Kelch-like protein 12, CUL3-interacting protein 1, DKIR homolog, hDKIR, KLHL12, C3IP1
Tested Applications
WB
Protein ID
97054498
Physical Properties
Liquid

Related Products

CatalogName
26-649KLHL32 Antibody
5223-002mgKLHL15 Antibody
5223-01mgKLHL15 Antibody
28-161KLHL14 Antibody
59-930KLHL14 Antibody
18-067KLHL11 Antibody
28-156KLHL13 Antibody
27-174KLHL15 Antibody
5223-01KLHL15 Antibody
3015-01mgKLHL1 Antibody

Alternative Products

CatalogName
GTR18161714-01KLHL12 Antibody

Popular Products