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SIT1 Antibody

CAT: 0223-58-721Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-721Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells. Involved in positive selection of T-cells.
NCBI Gene ID
27240
Swiss Prot
Q9Y3P8
Accession Number
Q9Y3P8
Host
Rabbit
Reactivity
Human
Immunogen
This SIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the C-terminal region of human SIT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
21 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SIT1
NCBI Official Name
Signaling threshold-regulating transmembrane adapter 1
NCBI Organism
Homo sapiens
Background Reference 01
Chapuis, J., et al. Mol. Psychiatry 14 (11) :1004-1016 (2009)
Background Reference 02
Tedoldi, S., et al. Blood 107 (1) :213-221 (2006)
Background Reference 03
Tao, W.A., et al. Nat. Methods 2 (8) :591-598 (2005)
Background Reference 04
Tao, W.A., et al. Nat. Methods 2 (8) :591-598 (2005)
Other Product Names
Signaling threshold-regulating transmembrane adapter 1, SHP2-interacting transmembrane adapter protein, Suppression-inducing transmembrane adapter 1, gp30/40, SIT1, SIT
Tested Applications
WB
Protein ID
74753488
Physical Properties
Liquid

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