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KRT3 Antibody

CAT: 0223-58-702Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-702Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
NCBI Gene ID
3850
Swiss Prot
P12035
Accession Number
P12035
Host
Rabbit
Reactivity
Human
Immunogen
This KRT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-441 amino acids from the Central region of human KRT3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
64 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KRT3
NCBI Official Name
Keratin, type II cytoskeletal 3
NCBI Organism
Homo sapiens
Background Reference 01
Szaflik, J.P., et al. Mol. Vis. 14, 1713-1718 (2008) :
Background Reference 02
Schweizer, J., et al. J. Cell Biol. 174 (2) :169-174 (2006)
Background Reference 03
Chen, Y.T., et al. Cornea 24 (8) :928-932 (2005)
Background Reference 04
Rogers, M.A., et al. J. Invest. Dermatol. 124 (3) :536-544 (2005)
Other Product Names
Keratin, type II cytoskeletal 3, 65 kDa cytokeratin, Cytokeratin-3, CK-3, Keratin-3, K3, Type-II keratin Kb3, KRT3
Tested Applications
WB
Protein ID
313104225
Physical Properties
Liquid

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