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TNNT2 Antibody

CAT: 0223-58-582Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-582Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
NCBI Gene ID
7139
Swiss Prot
P45379
Accession Number
P45379
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TNNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from the Central region of human TNNT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rb
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TNNT2
NCBI Official Name
Troponin T, cardiac muscle
NCBI Organism
Homo sapiens
Background Reference 01
Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010) :
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Millat, G., et al. EurMed Genet 53 (5) :261-267 (2010)
Background Reference 04
Watt, K.D., et al. Liver Transpl. 16 (8) :990-998 (2010)
Other Product Names
Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT, TNNT2
Tested Applications
WB
Protein ID
21264536
Physical Properties
Liquid

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