PLEKHF1 Antibody

CAT: 0223-58-549Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-549Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
NCBI Gene ID
79156
Swiss Prot
Q96S99
Accession Number
Q96S99
Host
Rabbit
Reactivity
Human
Immunogen
This PLEKHF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human PLEKHF1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PLEKHF1
NCBI Official Name
Pleckstrin homology domain-containing family F member 1
NCBI Organism
Homo sapiens
Background Reference 01
Chen, W., et al. J. Biol. Chem. 280 (49) :40985-40995 (2005)
Other Product Names
Pleckstrin homology domain-containing family F member 1, PH domain-containing family F member 1, Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains, Apoptosis-inducing protein, PH and FYVE domain-containing protein 1, Phafin-1, Zinc finger FYVE domain-containing protein 15, PLEKHF1, APPD, LAPF, ZFYVE15
Tested Applications
WB
Protein ID
115502559
Physical Properties
Liquid

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