ELK3 Antibody

• Background:

  The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present.

• NCBI Gene ID:

  2004

• Swiss Prot:

  P41970

• Accession Number:

  P41970

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ELK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of human ELK3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  44 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ELK3

• NCBI Official Name:

  ETS domain-containing protein Elk-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Serchov, T., et al. J. Biol. Chem. 285 (28) :21223-21232 (2010)

• Background Reference 02:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03:

  Li, B., et al. Tohoku J. Exp. Med. 216 (2) :139-147 (2008)

• Background Reference 04:

  Wasylyk, C., et al. Cancer Res. 68 (5) :1275-1283 (2008)

• Other Product Names:

  ETS domain-containing protein Elk-3, ETS-related protein ERP, ETS-related protein NET, Serum response factor accessory protein 2, SAP-2, SRF accessory protein 2, ELK3, NET, SAP2

• Tested Applications:

  WB

• Protein ID:

  116241349

• Physical Properties:

  Liquid