BAG5 Antibody

CAT: 0223-58-481Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-481Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BAG5 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.
NCBI Gene ID
9529
Swiss Prot
Q9UL15
Accession Number
Q9UL15
Host
Rabbit
Reactivity
Human
Immunogen
This BAG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human BAG5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
BAG5
NCBI Official Name
BAG family molecular chaperone regulator 5
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 02
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 03
Kalia, S.K., et al. Neuron 44 (6) :931-945 (2004)
Background Reference 04
Takayama, S., et al. J. Biol. Chem. 274 (2) :781-786 (1999)
Other Product Names
BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, BAG5, KIAA0873
Tested Applications
WB
Protein ID
12643895
Physical Properties
Liquid

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