ENOSF1 Antibody

• Background:

  ENOSF1 was originally identified as a naturally occurring antisense transcript to the human thymidylate synthase gene. Alternate splice variants have been described, one of which (named rTSalpha) represents an alternate 3'UTR that is complementary to the 3'UTR and terminal intron of the thymidylate synthase (TS) RNA and down-regulates TS expression. Other transcript variants (rTSbeta and rTSgamma) do not overlap the TS locus. The function of this gene appears to be primarily to regulate expression of the TS locus both via the antisense transcript as well as through the encoded proteins. [provided by RefSeq].

• NCBI Gene ID:

  55556

• Swiss Prot:

  Q7L5Y1

• Accession Number:

  Q7L5Y1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ENOSF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human ENOSF1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  50 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ENOSF1

• NCBI Official Name:

  Mitochondrial enolase superfamily member 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Giusti, B., et al. Thromb. Haemost. 104 (2) :231-242 (2010)

• Background Reference 02:

  Wang, Y., et al. J. Hum. Genet. 55 (8) :490-494 (2010)

• Background Reference 03:

  Cross, D.S., et al. BMC Genet. 11, 51 (2010) :

• Background Reference 04:

  Giusti, B., et al. J. Med. Genet. 45 (11) :721-730 (2008)

• Other Product Names:

  Mitochondrial enolase superfamily member 1, Antisense RNA to thymidylate synthase, rTS, L-fuconate dehydratase, ENOSF1, RTS, TYMSAS

• Tested Applications:

  WB

• Protein ID:

  74739173

• Physical Properties:

  Liquid