LIM2 Antibody

• Background :

  LIM2 is an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation.

• NCBI Gene ID :

  3982

• Swiss Prot :

  P55344

• Accession Number :

  P55344

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This LIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-137 amino acids from the C-terminal region of human LIM2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  20 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  LIM2

• NCBI Official Name :

  Lens fiber membrane intrinsic protein

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Ponnam, S.P., et al. Mol. Vis. 14, 1204-1208 (2008) :

• Background Reference 02 :

  Hsu, H., et al. Sheng Wu Gong Cheng Xue Bao 20 (4) :507-515 (2004)

• Background Reference 03 :

  Wistow, G., et al. Mol. Vis. 8, 171-184 (2002) :

• Background Reference 04 :

  Wistow, G., et al. Mol. Vis. 8, 185-195 (2002) :

• Other Product Names :

  Lens fiber membrane intrinsic protein, MP18, MP19, MP20, LIM2

• Tested Applications :

  WB

• Protein ID :

  17433717

• Physical Properties :

  Liquid