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TAF1A Antibody

CAT: 0223-58-292Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-292Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
NCBI Gene ID
9015
Swiss Prot
Q15573
Accession Number
Q15573
Host
Rabbit
Reactivity
Human
Immunogen
This TAF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from the N-terminal region of human TAF1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TAF1A
NCBI Official Name
TATA box-binding protein-associated factor RNA polymerase I subunit A
NCBI Organism
Homo sapiens
Background Reference 01
Greco-Stewart, V.S., et al. Virology 386 (1) :12-15 (2009)
Background Reference 02
Yamamoto, K., et al. Mol. Cell. Biol. 24 (14) :6338-6349 (2004)
Background Reference 03
Dynes, J.L., et al. J. Biochem. 135 (3) :429-438 (2004)
Background Reference 04
Hirschler-Laszkiewicz, I., et al. J. Biol. Chem. 278 (21) :18953-18959 (2003)
Other Product Names
TATA box-binding protein-associated factor RNA polymerase I subunit A, RNA polymerase I-specific TBP-associated factor 48 kDa, TAFI48, TATA box-binding protein-associated factor 1A, TBP-associated factor 1A, Transcription factor SL1, Transcription initiation factor SL1/TIF-IB subunit A, TAF1A
Tested Applications
WB
Protein ID
74739864
Physical Properties
Liquid

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