CD3G Antibody

• Background :

  CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in the CD3G gene are associated with T cell immunodeficiency.

• NCBI Gene ID :

  917

• Swiss Prot :

  P09693

• Accession Number :

  P09693

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CD3G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human CD3G.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  20 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  CD3G

• NCBI Official Name :

  T-cell surface glycoprotein CD3 gamma chain

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Siegers, G.M., J. Exp. Med. 204 (11), 2537-2544 (2007)

• Background Reference 02 :

  Sigalov, A.B., Biochemistry 45 (51), 15731-15739 (2006)

• Other Product Names :

  T-cell surface glycoprotein CD3 gamma chain, T-cell receptor T3 gamma chain, CD3g, CD3G, T3G

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  115993

• Physical Properties :

  Liquid