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DDX20 Antibody

CAT: 0223-58-056Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-056Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs.
NCBI Gene ID
11218
Swiss Prot
Q9UHI6
Accession Number
Q9UHI6
Host
Rabbit
Reactivity
Human
Immunogen
This DDX20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 713-741 amino acids from the C-terminal region of human DDX20.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
92 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DDX20
NCBI Official Name
Probable ATP-dependent RNA helicase DDX20
NCBI Organism
Homo sapiens
Background Reference 01
Todd, A.G., et al. J. Mol. Biol. 401 (5) :681-689 (2010)
Background Reference 02
Sun, X., et al. Cell Stress Chaperones 15 (5) :567-582 (2010)
Background Reference 03
Wilker, E.H., et al. Environ. Health Perspect. 118 (7) :943-948 (2010)
Background Reference 04
Boni, V., et al. Pharmacogenomics J. (2010) In press :
Other Product Names
Probable ATP-dependent RNA helicase DDX20, Component of gems 3, DEAD box protein 20, DEAD box protein DP 103, Gemin-3, DDX20, DP103, GEMIN3
Tested Applications
WB
Protein ID
12643886
Physical Properties
Liquid

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