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HSPBP1 Antibody

CAT: 0223-57-976Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-976Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HSPBP1 inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.
NCBI Gene ID
23640
Swiss Prot
Q9NZL4
Accession Number
Q9NZL4
Host
Rabbit
Reactivity
Human
Immunogen
This HSPBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-97 amino acids from the N-terminal region of human HSPBP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Symbol
HSPBP1
NCBI Official Name
Hsp70-binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Graner, M.W., et al. Cancer Sci. 100 (10) :1870-1879 (2009)
Background Reference 02
Evdonin, A., et al. Biol. Cell 101 (6) :351-360 (2009)
Background Reference 03
Souza, A.P., et al. Cell Stress Chaperones 14 (3) :301-310 (2009)
Background Reference 04
Howarth, J.L., et al. J. Neurochem. 108 (4) :945-951 (2009)
Other Product Names
Hsp70-binding protein 1, HspBP1, Heat shock protein-binding protein 1, Hsp70-binding protein 2, HspBP2, Hsp70-interacting protein 1, Hsp70-interacting protein 2, HSPBP1, HSPBP
Tested Applications
WB, IHC-P
Protein ID
74734730
Physical Properties
Liquid

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