IL25 Antibody

• Background:

  The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  64806

• Swiss Prot:

  Q9H293

• Accession Number:

  Q9H293

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This IL25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-104 amino acids from the Central region of human IL25.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  20 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  IL25

• NCBI Official Name:

  Interleukin-25

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Xu, G., et al. Allergy 65 (5) :581-589 (2010)

• Background Reference 02:

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 03:

  Goswami, S., et al. Nat. Immunol. 10 (5) :496-503 (2009)

• Background Reference 04:

  Caruso, R., et al. Blood 113 (15) :3512-3519 (2009)

• Other Product Names:

  Interleukin-25, IL-25, Interleukin-17E, IL-17E, IL25, IL17E

• Tested Applications:

  WB, IHC-P

• Protein ID:

  20138730

• Physical Properties:

  Liquid