CGB/hCG-Beta Antibody

• Background:

  This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG) . Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.

• NCBI Gene ID:

  1082936599402790000

• Swiss Prot:

  P01233

• Accession Number:

  P01233

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CGB/hCG-Beta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from the Central region of human CGB/hCG-Beta.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  18 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CGB

• NCBI Official Name:

  Choriogonadotropin subunit beta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cole, L.A. Placenta 31 (8) :653-664 (2010) Ra, Y.J., et al. Interact Cardiovasc Thorac Surg 11 (1) :114-116 (2010) Verma, B., et al. J. Immunol. 184 (4) :2156-2165 (2010) Handschuh, K., et al. Placenta 30 (12) :1016-1022 (2009) Reisenbichler, E.S., et al. Breast15 (5) :527-530 (2009)

• Other Product Names:

  Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta, CGB, CGB3

• Tested Applications:

  WB

• Protein ID:

  116184

• Physical Properties:

  Liquid