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ETV6 Antibody

CAT: 0223-57-766Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-766Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
NCBI Gene ID
2120
Swiss Prot
P41212
Accession Number
P41212
Host
Rabbit
Reactivity
Mouse
Immunogen
This ETV6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-202 amino acids from the Central region of human ETV6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ETV6
NCBI Official Name
Transcription factor ETV6
NCBI Organism
Homo sapiens
Background Reference 01
Otsubo, K., et al. Cancer Genet. Cytogenet. 202 (1) :22-26 (2010)
Background Reference 02
Roukens, M.G., et al. Nat. Cell Biol. 12 (10) :933-942 (2010)
Background Reference 03
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 04
Gascon, E., et al. J. Neurosci. 30 (37) :12414-12423 (2010)
Other Product Names
Transcription factor ETV6, ETS translocation variant 6, ETS-related protein Tel1, Tel, ETV6, TEL, TEL1
Tested Applications
WB
Protein ID
730927
Physical Properties
Liquid

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