USP15 Antibody

• Background:

  Ubiquitin (MIM 191339), a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs) . Also see USP1 (MIM 603478) .

• NCBI Gene ID:

  9958

• Swiss Prot:

  Q9Y4E8

• Accession Number:

  Q9Y4E8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This USP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-282 amino acids from the N-terminal region of human USP15.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  112 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  USP15

• NCBI Official Name:

  Ubiquitin carboxyl-terminal hydrolase 15

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Vos, R.M., et al. J. Virol. 83 (17) :8885-8892 (2009)

• Background Reference 03:

  Huang, X., et al. J. Mol. Biol. 391 (4) :691-702 (2009)

• Background Reference 04:

  Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

• Other Product Names:

  Ubiquitin carboxyl-terminal hydrolase 15, Deubiquitinating enzyme 15, Ubiquitin thioesterase 15, Ubiquitin-specific-processing protease 15, Unph-2, Unph4, USP15, KIAA0529

• Tested Applications:

  WB

• Protein ID:

  28381406

• Physical Properties:

  Liquid