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KCNK10 Antibody

CAT: 0223-57-588Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-588Size:400 µL
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Background
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq].
NCBI Gene ID
54207
Swiss Prot
P57789
Accession Number
P57789
Host
Rabbit
Reactivity
Human
Immunogen
This KCNK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 504-532 amino acids from the C-terminal region of human KCNK10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KCNK10
NCBI Official Name
Potassium channel subfamily K member 10
NCBI Organism
Homo sapiens
Background Reference 01
Gierten, J., et al. Br. J. Pharmacol. 154 (8) :1680-1690 (2008)
Background Reference 02
Huang, D., et al. Med. Hypotheses 70 (3) :618-624 (2008)
Background Reference 03
Goldstein, S.A., et al. Pharmacol. Rev. 57 (4) :527-540 (2005)
Background Reference 04
Gu, W., et al. J. Physiol. (Lond.) 539 (PT 3), 657-668 (2002) :
Other Product Names
Potassium channel subfamily K member 10, Outward rectifying potassium channel protein TREK-2, TREK-2 K (+) channel subunit, KCNK10, TREK2
Tested Applications
WB
Protein ID
13431412
Physical Properties
Liquid

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