MEF2D Antibody

• Background:

  MEF2D is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT] (4) TAR-3', found in numerous muscle-specific, growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity) .

• NCBI Gene ID:

  4209

• Swiss Prot:

  Q14814

• Accession Number:

  Q14814

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MEF2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-279 amino acids from the Central region of human MEF2D.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  56 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MEF2D

• NCBI Official Name:

  Myocyte-specific enhancer factor 2D

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Jablonski, K.A., et al. Diabetes 59 (10) :2672-2681 (2010)

• Background Reference 02:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 03:

  Aude-Garcia, C., et al. Biochem. J. 430 (2) :237-244 (2010)

• Background Reference 04:

  Czubryt, M.P., et al. J. Biol. Chem. 285 (22) :16942-16950 (2010)

• Other Product Names:

  Myocyte-specific enhancer factor 2D, MEF2D

• Tested Applications:

  WB

• Protein ID:

  2500876

• Physical Properties:

  Liquid