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DLX4 Antibody

CAT: 0223-57-441Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-441Size:400 µL
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Background
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
NCBI Gene ID
1748
Swiss Prot
Q92988
Accession Number
Q92988
Host
Rabbit
Reactivity
Human
Immunogen
This DLX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 amino acids from the Central region of human DLX4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DLX4
NCBI Official Name
Homeobox protein DLX-4
NCBI Organism
Homo sapiens
Background Reference 01
Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :
Background Reference 02
Schwartz, A.M., et al. Mod. Pathol. 22 (1) :1-6 (2009)
Background Reference 03
Man, Y.G., et al. Cancer Biomark 5 (1) :9-17 (2009)
Background Reference 04
Cavalli, L.R., et al. Cancer Genet. Cytogenet. 187 (1) :19-24 (2008)
Other Product Names
Homeobox protein DLX-4, Beta protein 1, Homeobox protein DLX-7, Homeobox protein DLX-8, DLX4, BP1, DLX7, DLX8, DLX9
Tested Applications
WB
Protein ID
85700416
Physical Properties
Liquid

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