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BIRC3 Antibody

CAT: 0223-57-421Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-421Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq].
NCBI Gene ID
330
Swiss Prot
Q13489
Accession Number
Q13489
Host
Rabbit
Reactivity
Human
Immunogen
This BIRC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the N-terminal region of human BIRC3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Symbol
BIRC3
NCBI Official Name
Baculoviral IAP repeat-containing protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Zane, L., et al. Virology 407 (2) :341-351 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Kim, C.W., et al. Biochem. Biophys. Res. Commun. 400 (1) :46-52 (2010)
Background Reference 04
Petersen, S.L., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (26) :11936-11941 (2010)
Other Product Names
Baculoviral IAP repeat-containing protein 3, 632-, Apoptosis inhibitor 2, API2, C-IAP2, IAP homolog C, Inhibitor of apoptosis protein 1, IAP-1, hIAP-1, hIAP1, RING finger protein 49, TNFR2-TRAF-signaling complex protein 1, BIRC3, API2, IAP1, MIHC, RNF49
Tested Applications
WB, IHC-P, IF
Protein ID
2497236
Physical Properties
Liquid

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