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VASP Antibody

CAT: 0223-57-408Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-408Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
NCBI Gene ID
7408
Swiss Prot
P50552
Accession Number
P50552
Host
Rabbit
Reactivity
Human
Immunogen
This VASP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-296 amino acids from the C-terminal region of human VASP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Symbol
VASP
NCBI Official Name
Vasodilator-stimulated phosphoprotein
NCBI Organism
Homo sapiens
Background Reference 01
Barragan, P., et al. Thromb. Haemost. 104 (2) :410-411 (2010)
Background Reference 02
Dittrich, M., et al. Arterioscler. Thromb. Vasc. Biol. 30 (4) :843-850 (2010)
Background Reference 03
Gan, L., et al. Mol. Immunol. 47 (6) :1278-1282 (2010)
Background Reference 04
Osmancik, P., et al. Catheter Cardiovasc Interv 75 (2) :158-166 (2010)
Other Product Names
Vasodilator-stimulated phosphoprotein, VASP, VASP
Tested Applications
WB, IHC-P
Protein ID
1718079
Physical Properties
Liquid

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