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RARA Antibody

CAT: 0223-57-306Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-306Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
NCBI Gene ID
5914
Swiss Prot
P10276
Accession Number
P10276
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This RARA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-349 amino acids from the C-terminal region of human RARA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Symbol
RARA
NCBI Official Name
Retinoic acid receptor alpha
NCBI Organism
Homo sapiens
Background Reference 01
Park, U.H., et al. J. Biol. Chem. 285 (44) :34269-34278 (2010)
Background Reference 02
Asleson, A.D., et al. Cancer Genet. Cytogenet. 202 (1) :33-37 (2010)
Background Reference 03
Catalano, A., et al. Blood 110 (12) :4073-4076 (2007)
Background Reference 04
Wells, R.A., et al. Nat. Genet. 17 (1) :109-113 (1997)
Other Product Names
Retinoic acid receptor alpha, RAR-alpha, Nuclear receptor subfamily 1 group B member 1, RARA, NR1B1
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
133483
Physical Properties
Liquid

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