ABHD4 Antibody

• Background:

  Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE) . Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine (By similarity) .

• NCBI Gene ID:

  63874

• Swiss Prot:

  Q8TB40

• Accession Number:

  Q8TB40

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This ABHD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-127 amino acids from the Central region of human ABHD4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ABHD4

• NCBI Official Name:

  Abhydrolase domain-containing protein 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Simon, G.M., et al. J. Biol. Chem. 281 (36) :26465-26472 (2006)

• Other Product Names:

  Abhydrolase domain-containing protein 4, 311-, Alpha/beta-hydrolase 4, Lyso-N-acylphosphatidylethanolamine lipase, ABHD4

• Tested Applications:

  WB, IHC-P

• Protein ID:

  74762601

• Physical Properties:

  Liquid