CORO2A Antibody

CAT: 0223-57-143Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-143Size:400 µL
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Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
NCBI Gene ID
7464
Swiss Prot
Q92828
Accession Number
Q92828
Host
Rabbit
Reactivity
Human
Immunogen
This CORO2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the Central region of human CORO2A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CORO2A
NCBI Official Name
Coronin-2A
NCBI Organism
Homo sapiens
Background Reference 01
Jin, Y., et al. Nat. Genet. 42 (7) :576-578 (2010)
Background Reference 02
Marshall, T.W., et al. J. Cell. Sci. 122 (PT 17), 3061-3069 (2009) :
Background Reference 03
Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)
Background Reference 04
Yoon, H.G., et al. Mol. Cell 12 (3) :723-734 (2003)
Other Product Names
Coronin-2A, IR10, WD repeat-containing protein 2, CORO2A, IR10, WDR2
Tested Applications
WB
Protein ID
28381354
Physical Properties
Liquid

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