USP40 Antibody

• Background:

  Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]) .

• NCBI Gene ID:

  55230

• Swiss Prot:

  Q9NVE5

• Accession Number:

  Q9NVE5

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This USP40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the N-terminal region of human USP40.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  140 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  USP40

• NCBI Official Name:

  Ubiquitin carboxyl-terminal hydrolase 40

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wu, Y.R., et al. Clin. Chim. Acta 411 (13-14), 955-958 (2010) :

• Background Reference 02:

  Li, Y., et al. Hum. Mutat. 27 (10) :1017-1023 (2006)

• Background Reference 03:

  Hillier, L.W., et al. Nature 434 (7034) :724-731 (2005)

• Background Reference 04:

  Quesada, V., et al. Biochem. Biophys. Res. Commun. 314 (1) :54-62 (2004)

• Other Product Names:

  Ubiquitin carboxyl-terminal hydrolase 40, Deubiquitinating enzyme 40, Ubiquitin thioesterase 40, Ubiquitin-specific-processing protease 40, USP40

• Tested Applications:

  WB

• Protein ID:

  59803114

• Physical Properties:

  Liquid