LDHA Antibody

• Background:

  The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.

• NCBI Gene ID:

  3939

• Swiss Prot:

  P00338

• Accession Number:

  P00338

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This LDHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the C-terminal region of human LDHA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  37 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  LDHA

• NCBI Official Name:

  L-lactate dehydrogenase A chain

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

• Background Reference 02:

  Zhu, X., et al. Genet. Epidemiol. 34 (2) :171-187 (2010)

• Background Reference 03:

  Zhuang, L., et al. Mod. Pathol. 23 (1) :45-53 (2010)

• Background Reference 04:

  Zhao, Y.H., et al. Oncogene 28 (42) :3689-3701 (2009)

• Other Product Names:

  L-lactate dehydrogenase A chain, LDH-A, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59, LDHA

• Tested Applications:

  WB, IHC-P, IF

• Protein ID:

  126047

• Physical Properties:

  Liquid